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. 2018 Nov 24;3(1):e000104. doi: 10.1136/bmjophth-2017-000104

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© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Confocal and split-detector AOSLO subclinical photoreceptor mosaic anomalies. Focal regions of abnormal waveguiding photoreceptors were found in confocal AOSLO foveal mosaics in subjects JC_10451 OD & OS, CW_10303 OS and SR_10341 OS (white boxes). Magnified views of these regions show focal hyper-reflective waveguiding cones with confocal AOSLO imaging (A–F) and focal mounding of photoreceptor inner-segment structure on split-detector AOSLO imaging (A_split–F_split), ranging from 25 µm to 40 µm in size. Montages: scale bar=300 µm. A–F_split: scale bar=40 µm. AOSLO, adaptive optics scanning light ophthalmoscopy.