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. 2018 Nov 24;3(1):e000104. doi: 10.1136/bmjophth-2017-000104

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© Author(s) (or their employer(s)) 2018. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

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Confocal and split-detector AOSLO imaging in areas of photoreceptor mosaic disruption in subject KS_0552. Foveal confocal AOSLO revealed multiple areas of non-waveguiding cone photoreceptors (A). Three of these regions (A1–A3) were compared with aligned corresponding split-detector images (B1–B3). Areas of both absent inner-segment structure (B1, black arrow) and remnant inner-segment photoreceptor structure (B2, B3, white arrows) were present in these areas of non-waveguiding confocal images. A–B3: scale bar=25 µm. AOSLO, adaptive optics scanning light ophthalmoscopy.