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. 2018 Sep 19;16(6):4609–4615. doi: 10.3892/etm.2018.6766

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Copyright: © Hu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Total numbers of splenic Tregs are significantly decreased during heat stroke. (A) Splenic Tregs are defined as CD4⁺Foxp3⁺ splenocytes in FACs. (B) The percentage of Tregs decreased in the HS group at 0, 24 and 72 h time intervals post-heat stress compared with the NC group. Data are expressed as the mean ± standard deviation. *P<0.05 and **P<0.01 vs. NC. NC, negative control; HS, heatstroke; CD, cluster of differentiation, Foxp3, forkhead/winged-helix transcription factor; Tregs, T regulatory cells; APC, allophycocyanin; FITC, fluorescein isothiocyanate.