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. 2010 Jun 1;15(6):3932–3957. doi: 10.3390/molecules15063932

Table 3.

Results of antitumor cytotoxicity for some synthesized thienopyrimidines.

Comp. No Cytotoxicity IC50 (μg/mL)
HEPG2 HELA MCF7 HCT116 HEP2
4a 2.35 1.07 2.82 2.01 1.61
7d 1.28 1.41 0.67 0.47 0.47
8a 0.94 0.87 0.74 - 0.47
12 0.74 0.81 1.54 2.68 0.81
15 1.21 0.40 0.6 1.68 0.54
29 0.40 0.60 0.94 2.89 1.14
42 1.81 0.81 2.48 0.54 1.14
Doxorubicin 0.54 0.85 0.7 0.69 0.4