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Cleavage reactions of 5’UTR by ribozymes and chimeric RNA molecules. Each gel autoradiograph shows a representative cleavage reaction time course of a specific ribozyme and its respective DIS and αDIS derived chimeras: (a) HH113, (b) HH159, (c) HP113 and (d) HP159. Each experiment was performed in triplicate and the cleavage percentage was obtained by quantification of the cleavage products. Curves were fitted with maximum sqr(R) coefficients.
