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. 2018 Oct 10;61(22):9952–9965. doi: 10.1021/acs.jmedchem.8b00883

Table 3. Oral Exposure of P01 in Mice after a Single Dose.

PK propertya unit P01
Cmax μg/mL 0.25
Tmax h 1.0
T1/2 h 4.1
AUC μg·h/mL 1.06
Vd L/kg 33.7
CL μg/h 9.48
a

Pharmacokinetic parameters of P01 in C57Bl/6 mice dosed orally with 10 mg/kg.