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. 2018 Sep 18;16(6):4393–4400. doi: 10.3892/etm.2018.6751

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Copyright: © Yu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Flow chart of the study design and recruitment of study subjects. Patients with CHB (n=740) from Huashan Hospital affiliated to Fudan University (Shanghai, China; n=330) and the First Hospital of Quanzhou affiliated to Fujian Medical University (Quanzhou, China; n=410) were evaluated. A total of 356 patients with alanine aminotransferase ≤2 upper limit of normal were included in the present study and were randomly divided into an experimental assessment cohort (n=238) and a validation cohort (n=118) at a ratio of 2:1. Histological grading of liver necroinflammation was performed according to the Scheuer scoring system. HCC, hepatocellular carcinoma; CHB, chronic hepatitis B.