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. 2018 Sep 18;16(6):4393–4400. doi: 10.3892/etm.2018.6751

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Copyright: © Yu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Receiver operating characteristic curves of non-invasive biomarkers, including the ATAR ratio and the levels of AST, ALB, ALT and GLB for prediction of significant liver necroinflammation in HBeAg⁺ patients with (A) ALT ≤2 ULN (the cut-off values were as follows: 0.617 for ATAR, 41.9 for ALB, 30 for GLB, 22 for ALT and 29 for AST), (B) HBeAg⁻ patients with ALT ≤2 ULN (the cut-off values were as follows: 0.830 for ATAR, 43 for ALB, 34 for GLB, 37 for ALT and 25 for AST), (C) HBeAg⁺ patients with ALT ≤1 ULN (the cut-off values were as follows: 0.617 for ATAR, 42.9 for ALB, 30 for GLB, 32 for ALT and 16 for AST) and (D) HBeAg⁻ patients with ALT ≤1 ULN (the cut-off values were as follows: 0.5 for ATAR, 42. for ALB, 34 for GLB, 26 for ALT and 18 for AST). AST, aspartate aminotransferase; ATAR, AST to ALB ratio; ALB, albumin; ALT, aminotransferase; GLN, globulin; ULN, upper limit of normal; AUC, area under curve; CI, confidence interval; HBeAg, hepatitis B e antigen.