Figure 7.

miR-21-5p promotes NSCLC cell proliferation by targeting TGFBI. (A) Cell proliferation curve of A549 cells transfected with the control mimic plus the control plasmid, the control mimic plus the TGFBI overexpressing plasmid, the miR-21-5p mimic plus the control plasmid, or the miR-21-5p mimic plus the TGFBI overexpressing plasmid. (B and C) EdU assays performed in cells described in (A), and the EdU positive cells were observed at 565 nm using a fluorescence inverted microscope (magnification, ×200). (B) Quantitative analysis; (C) representative images. The results were expressed as mean ± SD of three independent experiments (n=3; *P<0.05; **P<0.01; ***P<0.001). NSCLC, non-small cell lung cancer.