Table III.
Association of SNP genotypes with IS susceptibility.
| Genotype | Control (n=300) | Cases (n=308) | OR (95% CI) | P value |
|---|---|---|---|---|
| rs1801133 | ||||
| TT | 101 (36.7) | 106 (36.7) | 1 | |
| TC | 125 (45.5) | 127 (42.8) | 0.96 (0.62–1.47) | 0.841 |
| CC | 49 (17.8) | 64 (21.5) | 1.18 (0.69–2.00) | 0.546 |
| Dominant | 0.95 (0.64–1.40) | 0.782 | ||
| Additive | 1.07 (0.82–1.38) | 0.625 | ||
| rs11018628 | ||||
| TT | 134 (47.0) | 210 (68.2) | 1 | |
| TC | 87 (30.5) | 88 (28.6) | 0.56 (0.36–0.86) | 0.008 |
| CC | 64 (22.5) | 10 (3.2) | 0.08 (0.04–0.18) | <0.001 |
| Dominant | 0.32 (0.22–0.48) | <0.001 | ||
| Additive | 0.37 (0.28–0.50) | <0.001 | ||
| rs12645561 | ||||
| CC | 162 (53.4%) | 163 (50.9%) | 1.00 | |
| CT | 122 (40.3%) | 124 (38.8%) | 0.97 (0.66–1.44) | 0.898 |
| TT | 19 (6.3%) | 33 (10.3%) | 1.72 (0.85–3.49) | 0.132 |
| Dominant | 1.07 (0.74–1.55) | 0.707 | ||
| Additive | 1.15 (0.87–1.54) | 0.328 | ||
Logistic regression analyses adjusted for age, sex, smoking, drinking, diabetes, hypertension, and total cholesterol.