Skip to main content
. 2010 Aug 27;15(9):5878–5908. doi: 10.3390/molecules15095878

Table 1.

Approved anti-HBV drugs.

Molecule Structure Brand name Mechanism Company Year of FDA approval
Lamivudine graphic file with name molecules-15-05878-i001.jpg Zeffix, Heptovir, Epivir, and Epivir-HBV Nucleoside analogue/RT Inhibitor GlaxoSmithKline 1998 (for adults) and 2000 (for children) in US
Adefovir graphic file with name molecules-15-05878-i002.jpg Preveon and Hepsera Nucleotide analogue/RT Inhibitor Gilead 2002 (US)
Entecavir graphic file with name molecules-15-05878-i003.jpg Baraclude Nucleoside analogue/RT Inhibitor Bristol Meyers Squibb 2005 (US)
Telbivudine graphic file with name molecules-15-05878-i004.jpg Sebivo (Europe) Tyzeka (US) Nucleoside analogue/RT Inhibitor Idenix, Novartis 2006 (US)
Clevudine graphic file with name molecules-15-05878-i005.jpg Levovir and Revovir Nucleoside analogue/RT Inhibitor. Bukwang Pharm 2006 (KOREA)
Tenofovir graphic file with name molecules-15-05878-i006.jpg Viread Nucleotide analogue/RT Inhibitor Gilead 2008 (US)