Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Nov 6;43(1):358–370. doi: 10.3892/ijmm.2018.3980

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

miR-138 expression affects endometriosis in a co-culture with THP-1 cells and ESCs through NF-κB expression. (A) miR-138 was identified in the 3′-untranslated region of p65, and (B) immunofluorescence revealed that NF-κB expression was suppressed in THP-1 cells (magnification, ×40). (C) Western blot analysis showing that overexpression of miR-138 affects Bax, NF-κB and VEGF protein levels; quantified protein expression levels of (D) Bax, (E) VEGF and (F) NF-κB are shown. (G) Downregulation of miR-138 expression affects Bax, NF-κB and VEGF protein levels are determined by western blot assay; quantified results of (H) Bax, (I) VEGF and (J) NF-κB protein expression levels are shown. ^##P<0.01 vs. negative control group. miR, microRNA; Bax, B-cell lymphoma 2-associated X protein; NF-κB, nuclear factor-κB; VEGF, vascular endothelial growth factor; miR-138, overexpression group; anti-138, downregulation group.

miR-138 expression affects endometriosis in a co-culture with THP-1 cells and ESCs through NF-κB expression. (A) miR-138 was identified in the 3′-untranslated region of p65, and (B) immunofluorescence revealed that NF-κB expression was suppressed in THP-1 cells (magnification, ×40). (C) Western blot analysis showing that overexpression of miR-138 affects Bax, NF-κB and VEGF protein levels; quantified protein expression levels of (D) Bax, (E) VEGF and (F) NF-κB are shown. (G) Downregulation of miR-138 expression affects Bax, NF-κB and VEGF protein levels are determined by western blot assay; quantified results of (H) Bax, (I) VEGF and (J) NF-κB protein expression levels are shown. ^##P<0.01 vs. negative control group. miR, microRNA; Bax, B-cell lymphoma 2-associated X protein; NF-κB, nuclear factor-κB; VEGF, vascular endothelial growth factor; miR-138, overexpression group; anti-138, downregulation group.