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. 2018 Oct 29;43(1):285–293. doi: 10.3892/ijmm.2018.3963

Figure 4.

Figure 4

Effects of chidamide and VPA on the apoptosis of multiple myeloma cells after 48 h, as determined by flow cytometry using Annexin V-FITC/PI staining. Effects of various concentrations of chidamide on the apoptosis of (A) U266 and (B) RPMI8226 cells. Effects of various concentrations of VPA on the apoptosis of (C) U266 and (D) RPMI8226 cells. (E) Chidamide and VPA could promote apoptosis of U266 and RPMI8226 cells after 48 h; the apoptotic rate was increased with increasing drug concentrations. *P<0.05, **P<0.01 vs. the untreated control group. FITC, fluorescein isothiocyanate; PI, propidium iodide; VPA, valproic acid.