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. 2018 Oct 23;43(1):103–116. doi: 10.3892/ijmm.2018.3950

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Copyright: © Jiang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Silencing the expression of Galectin-1 increases cell apoptosis and delays cell cycle progression in mouse hepatic stellate cells. (A) Flow cytometric analysis and (B) quantification showed that a low the expression of Galectin-1 suppressed cell cycle progression. (C) Flow cytometric analysis confirmed that a low expression of Galectin-1 accelerated cell apoptosis; (D) apoptotic rate in each group; (E) Bcl-2, cleaved caspase-3 and caspase-3 protein bands in each group; (F) levels of Bcl-2 and cleaved caspase-3/caspase-3 in each group; ^*P<0.05 vs. normal group; ^#P<0.05 vs. model group. sh, short hairpin RNA; NC, negative control; Bcl-2, B-cell lymphoma-2; GAPDH, glyceraldehyde-3-phosphate dehydrogenase.