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. 2018 Nov 13;2018:2525173. doi: 10.1155/2018/2525173

Table 1.

Virulence factor requirement during different ocular infectious diseases.

Virulence factor Conjunctivitis Keratitis Endophthalmitis
(reference) (reference) (reference)
Polysaccharide capsule dispensable [7, 15, 64, 68, 112] dispensable [7, 9] necessary [105]

Pneumolysin (PLY) Unknown necessary [9, 32, 34] necessary [25, 36, 37, 106]

Neuraminidase necessary [7, 68] necessary [7, 61] unknown [108]

Zinc metalloproteinase C (ZmpC) necessary [54, 55] necessary [55] unknown