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. 2018 Nov 2;14:25–32. doi: 10.1016/j.ctro.2018.10.005

Fig. 4.

Fig. 4

The dose-response curve of biologically effective dose (BEDH) converted from high-LET carbon-ions in development of pulmonary fibrosis (shown as black squares). The dose-dependency of RBE with reference to increasing BEDH was also revealed (shown as red circles). BEDH for carbon-ions resulting in half maximum fibrosis (BEDED50) was estimated as 58.12 Gy; whereas RBE at this BEDED50 level was estimated as 2.88.