Table 5.
Toxicities associated with treatment
| toxicities | CCRT(N = 55) | chemotherapy(N = 86) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Gr.1 | Gr.2 | Gr.3 | Gr.4 | ≥Gr. 3 | Gr.1 | Gr.2 | Gr.3 | Gr.4 | ≥Gr. 3 | P | |
| Leucocytopenia | 11 (20.0%) | 17 (30.9%) | 19 (34.5%) | 4 (7.3%) | 41.8% | 19 (22.1%) | 43 (50.0%) | 16 (18.6%) | 5 (5.8%) | 24.4% | 0.040 |
| Thrombocytopaenia | 27 (49.1%) | 12 (21.8%) | 6 (10.9%) | 0 (0.0%) | 10.9% | 45 (52.3%) | 24 (27.9%) | 7 (8.1%) | 1 (1.2%) | 9.3% | 0.779 |
| Anemia | 37 (67.3%) | 9 (16.4%) | 1 (1.8%) | 0 (0.0%) | 1.8% | 52 (60.5%) | 15 (17.4%) | 1 (1.2%) | 0 (0.0%) | 1.2% | 0.647 |
| Nausea/vomiting | 28 (50.9%) | 16 (29.1%) | 2 (3.6%) | 0 (0.0%) | 3.6% | 47 (54.7%) | 16 (18.6%) | 6 (7.0%) | 0 (0.0%) | 7.0% | 0.483 |
| liver injury | 6 (10.9%) | 1 (1.8%) | 0 (0.0%) | 0 (0.0%) | 0% | 10 (11.6%) | 2 (2.3%) | 0 (0.0%) | 0 (0.0%) | 0% | – |
| treatment-related pneumonitis | 19 (34.5%) | 7 (12.7%) | 4 (7.3%) | 0 (0.0%) | 7.3% | – | – | – | – | – | |
| treatment-related esophagitis | 24 (43.6%) | 16 (29.1%) | 8 (14.5%) | 0 (0.0%) | 14.5% | – | – | – | – | – | |
Abbreviations: CCRT concurrent chemoradiotherapy, Gr grade