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. 2018 Nov 26;37:283. doi: 10.1186/s13046-018-0953-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — EBV-miR-BART8-3p expression is upregulated and co-expressed in NPC. a Heat map of 86 miRNAs differentially expressed between NPC specimens and normal nasopharyngeal mucosal specimens (CTRL). b Topological overlap matrix (TOM) plot of the microRNA co-expression network. The x- and y-axes represent 1315 microRNAs and the color intensity indicates interaction strength between microRNAs with red for the strongest interaction and white for no interaction. The color bars along the x- and y-axes denote the module membership. c The 20 most highly upregulated EBV BART miRNAs identified between NPC specimens and normal nasopharyngeal mucosal specimens