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. 2018 Nov 26;37:283. doi: 10.1186/s13046-018-0953-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — EBV-miR-BART8-3p promotes NPC cell migration and invasion in vitro and lung metastasis in vivo. a qPCR assay reveals higher EBV-miR-BART8-3pexpression in NPC specimens than in normal nasopharyngeal mucosal specimens (CTRL). b qPCR assay reveals higher EBV-miR-BART8-3p expression in NPC cells transfected withEBV-miR-BART8-3p precursors than in those transfected with control vectors. miRNA levels are normalized to U6 snRNA expression. c Representative images and quantification of the wound-healing assay in CNE-1 andSUNE-1cells. d Representative images and quantification of migration and invasion assays in CNE-1 andSUNE-1. e Representative images and quantification of the wound-healing assay in C666–1 cells. f Representative images and quantification of migration and invasion assays in C666–1 cells. ND, not detectable. Data is presented as the mean ± SD. ** P < 0.01; *** P < 0.001