Table 1.
Variable | COPD risk cohort (n = 74) |
Normal healthy cohort (n = 41) |
---|---|---|
Agea | 59 ± 8 | 26 ± 3g |
Gender (Female)b | 47 (63.5%) | 19 (46.3%) |
Height (m) | 1.63 ± 0.08 | 1.69 ± 0.09 (1) |
Weight (kg) | 63.7 ± 8.3 | 60.7 ± 9.7 (1) |
Smoke (Yes) | 14 (18.9%) (7) | 2 (4.9%) |
FEV1 (L) | 2.28 ± 0.40 (3) | |
FEV1% predicted | 91.2 ± 12.3 (3) | |
FVC (L) | 2.72 ± 0.50 (3) | |
FVC% predicted | 88.2 ± 14.8 (3) | |
FEV1/FVC ratio (%) | 84.1 ± 6.4 (3) | |
CATc | 11.0 ± 3.4 (5) | |
mMRCd | 0.3 ± 0.5 (6) | |
CCQe | 3.0 ± 4.8 (5) | |
Airway bacteria loadf | 119.5 ± 188.2 |
Values shown for continuous variables are mean ± S.D. The number of missing data is shown in parentheses if there is any.
Values shown for categorical variables are the number of samples along with percentage shown in the parentheses. The number of missing data is shown in the subsequent parentheses if there is any.
CAT: COPD Assessment Test score.
mMRC: modified Medical Research Council dyspnea scale.
CCQ: Clinical COPD Questionnaire score.
defined in Formula 1.
Since the sputum sample for 16S sequencing in normal healthy cohort were collected at multiple time points during 2016–2017, the age for each subject is calculated as the mean value across time points.