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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: J Hepatol. 2018 Jun 13;69(2):534–543. doi: 10.1016/j.jhep.2018.05.001

Fig. 1. Algorithm for diagnosis of alcoholic hepatitis.

Fig. 1.

*Clinical criteria: Heavy alcohol use (>2 drinks in females and >3 drinks in males) for >5 years; Active alcohol use until at least 8 weeks prior to presentation; Recent (<1 month) onset or worsening of jaundice; Exclude other liver diseases, biliary obstruction, HCC. *Biochemical criteria: Serum bilirubin >3 mg/dl, AST >50 and <500, AST >ALT by 1.5:1; **Transjugular route preferred for obtaining the liver tissue. **Characteristic histological findings: Cell balooning, neutrophil infiltration, cholestasis, varying degree of steatosis and fibrosis. ***Needed for inclusion in clinical trials and before starting specific pharmacologic therapy. AH, alcoholic hepatitis; ALT, alanine aminotransferase; AST, aspartate aminotransferase; HCC, hepatocellular carcinoma.