Table 4.
Mortality and morbidity of neonates who underwent surgery due to necrotizing enterocolitis.
| Center 1 | Center 2 | p-value | ||
|---|---|---|---|---|
| (n=18) | (n=6) | |||
| Gestational age (weeks) as median, mean ± SD | 25 (24.9; 1.54) | 27.5 (27.35; 3.98) | 0.04 | |
|
| ||||
| Birth weight (gram) as median mean ± SD | 759 (746.4; 230.7) | 775 (805; 362) | 0.65 | |
|
| ||||
| SGA (%) | 22.2 | 50.0 | 0.31 | |
|
| ||||
| Male gender (%) | 44.4 | 66.7 | 0.64 | |
|
| ||||
| Singletons (%) | 83.3 | 100 | 0.55 | |
|
| ||||
| Prenatal steroids (%) | 77.8 | 50.0 | 0.31 | |
|
| ||||
| Amnion infection synd. (%) | 25.0 | 33.3 | 0.99 | |
|
| ||||
| IVH (grade 3-4, %) | 12.5 | 33.3 | 0.29 | |
|
| ||||
| RPM (grade 3-4, %) | 26.7 | 33.3 | 0.99 | |
|
| ||||
| BPD (grade 2-3, %) | 46.2 | 16.7 | 0.60 | |
|
| ||||
| Death (%) | 22.2 | 0 | 0.28 | |
|
| ||||
| Time between NPO and first contact with surgeon (days) as mean ± SD | 1.824 (2.4) | 0.1667 (0.6) | 0.008 | |
|
| ||||
| Length of removed intestine (cm) as median, mean ± SD | 39 (49.96; 36.7) | 11 (19.5; 17.25) | 0.043 | |
|
| ||||
| Abdominal surgical procedures per patient as median, mean ± SD | 3 (2.6; 0.8281) | 2 (2.6; 0.8944) | 0.99 | |
|
| ||||
| Short bowel syndrome (%) | 38.9 | 0 | 0.03 | |
|
| ||||
| Exclusively human milk (%) | 27.7 | 33.3 | 0.99 | |
|
| ||||
| Human milk combined with formula (%) | 27.7 | 33.3 | 0.99 | |
|
| ||||
| Exclusively formula milk (%) | 44.4 | 33.3 | 0.99 | |
|
| ||||
| Amount of oral feeds in ml/kg/die (median, mean ± SD) | on day 5 | 46 (45.4; 20.3) | 42.5 (41.7; 39.53) | 0.74 |
| on day 10 | 78 (73.3; 45.7) | 82.5 (82.5; 67.3) | 0.73 | |
| on day 15 | 71 (62.5; 71.6) | 72 (84.5; 61.1) | 0.33 | |
|
| ||||
| Prophylaxis with probiotics (%) on day 14 of life | 76,5 | 83,3 | 0.99 | |