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. 2018 Nov 13;2018:6816508. doi: 10.1155/2018/6816508

Figure 2.

Figure 2

β3-AR/UCP2 axis blockade affects the glycolytic metabolism of both A375 and ES cells. Western blot analysis of UCP2 marker after treatment with BRL37344 (10 μM) + genipin (15 μM), BRL37344 (10 μM), and BRL37344 (10 μM) + SR59230A (10 μM) (a, e). Glucose uptake and lactate export assays (b, f). WB analysis of HKII and MCT-4 markers (c, g). ATP production assay (d, h). Data are representative of at least three experiments (mean and SD). P values for SR59230A treatment ∗ P < 0.05, ∗∗ P < 0.01, and ∗∗∗ P < 0.001. P values for genipin treatment: # P < 0.05, ## P < 0.01, and ### P < 0.001.