Table 2.
Area of decreased amplitude of low frequency fluctuation (ALFF) and altered functional connectivity (FC) in female subjects with major depressive disorder compared to healthy controls
| Metrics | Brain region (BA area) | Cluster size | MNI coordinates | T values | ||
|---|---|---|---|---|---|---|
| X | Y | Z | ||||
| ALFF | Left Middle Occipital Gyrus (BA37)(L-MOG) | 159 | −30 | −93 | 3 | −2.90 |
| L-MOG seed FC | Left Medial Prefrontal Gyrus(BA9/10)(L-mPFG) | 115 | −6 | 57 | 18 | 3.44 |
| Left Hippocampus (BA21) | 112 | −33 | −33 | −9 | 5.09 | |
| Left Orbitofrontal cortex (BA11/47) (L-OFC) | 85 | −12 | 33 | −27 | −4.14 | |
Abbreviations: BA Brodmann area, MNI Montreal Neurologic Institute