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. 2018 Nov 6;5:1124–1128. doi: 10.1016/j.toxrep.2018.11.006

Table 3.

Blood counts in rats at the end of 14 days of treatment.

Analyte Vehicle Acrylamide
25 mg/kg
Acrylamide
50 mg/kg
Reference intervals+
Erythrocytes 8.00 ± 0.09 4.79 ± 0.63* 3.44 ± 0.11* 7.80- 8.65 103/mm3
Hb 14.34 ± 0.12 9.35 ± 1.04* 9.23 ± 0.10* 13.20-17.10 g/dl
Hto 43.35 ± 0.68 28.51 ± 3.67* 30.70 ± 0.32* 35-45%
MCV 53.60 ± 0.76 41.28 ± 2.11* 32.33 ± 0.86* 45.00- 65.00 fl
MCH 17.70 ± 0.27 18.25 ± 0.73 18.03 ± 0.41 15.53-20.05 pg
MCHC 32.81 ± 0.34 32.52 ± 0.63 32.33 ± 0.62 25.88-32.88 g/dl
Leukocytes 6.71 ± 0.52 3.93 ± 0.71* 3.75 ± 0.23* 4.00-17.00 103/mm3
Platelets 736.14 ± 49.53 297.14 ± 94.23* 226.66 ± 3.05* 300.00-1500.00 103/mm3

The data are expressed as mean ± SEM.

*

p <  0.05, vs. vehicle group (one-way ANOVA for independent groups followed by Student-Newman-Keuls post hoc test).

+

Source: Vaquero [32], Arcila et al. [33].