Fig. 2.

3D and 2D visualizations of disease-related alteration negentropy maps. The top panel (A) shows cortical normalized alteration negentropy (A-negentropy) maps related to the ICD-10 pathological categories (for detailed information see also Table 3). The middle panel (B) shows the cortical areas with the highest A-negentropy (i.e., the 10% with the highest values). These areas match with sensorimotor, visual, inferior temporal, and supramarginal regions. The bottom panel (C) shows subcortical normalized A-negentropy maps related to the ICD-10 pathological categories. Of note, a large part of the white matter sites show a high A-negentropy values; this result, however, is to be expected, as we queried the BrainMap database for gray matter alterations only.