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. 2018 Nov 26;15:24. doi: 10.1186/s12950-018-0200-0

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Lutein pre-treatment attenuates the number of Cox-2-immunoreactive cells in whisker pad among naïve, inflamed, and inflamed with lutein administration rats. a Naïve rats, b CFA-induced inflamed rats, c Inflamed rats 3 days after treatment (10 mg/kg, i.p.). d Comparison of the number of Cox-2-immunoreactive cells in the orofacial skin among three groups of rats. *, P < 0.05, naïve vs. inflamed rats and inflamed vs. inflamed with lutein. e Comparison of the mean percentage of Cox-2-immunoreactive cells in the orofacial skin among three groups of rats. *, P < 0.05, naïve vs. inflamed rats and inflamed vs. inflamed with lutein, n = 3