Table 2.

In-vivo imaging protocol

(a) Brain Imaging
IR FSE (Reference T1 mapping) (8min48s)	FOV = 28cm × 28cm, In-plane resolution = 1.1mm × 1.75 mm Slice thickness = 5mm, Average = 1, Bandwidth = $\pm$15.63kHz, TR=6s TI = [50, 200, 350, 425, 500, 750, 900, 1100] ms
Multi-TE SE (Reference T2 mapping) (10min10s)	FOV = 28cm × 28cm, In-plane resolution = 2.2mm × 2.2 mm Parallel imaging factor = 2, Slice thickness = 5mm, Bandwidth = $\pm$62.5kHz, TR=1.8s TE = [30, 60, 90, 120, 150] ms
STE-DWI (Reference ADC mapping) (1min40s)	FOV = 28cm × 28cm, Resolution = 2.2mm × 2.2 mm, Parallel imaging factor = 2, Slice thickness = 5mm, Bandwidth = $\pm$62.5kHz, TR=4s, Diffusion direction = R/L, TM=100ms, TE =40ms, b== [50, 100, 200(2), 400(4), 600(6), 800(8)] s/mm2
STEM (13min20s)	TM = 25ms, TE = 49ms	FOV = 28cm × 28cm, Resolution = 2.2mm × 2.2 mm Parallel imaging factor = 2, Slice thickness = 5mm, Bandwidth = $\pm$62.5kHz, TR=4s Diffusion direction = R/L, Same b-values as STE-DWI
	TM = 100ms, TE = 40ms
	TM = 100ms, TE = 50ms
	TM = 100ms, TE = 80ms
	TM = 500ms, TE = 40ms
	TM = 500ms, TE = 50ms
	TM = 500ms, TE = 80ms
	TM = 1000ms, TE = 40ms

(b) Prostate Imaging
DESPOT1 with B1 correction (Reference T1 mapping) (4min36s)	FOV = 28cm×28×14cm, In-plane resolution = 0.8mm × 0.57 mm Slice thickness = 5mm, Average = 4, Bandwidth = $\pm$62.5kHz, TR=4s Flip angle = [ ${10}^{\circ }$, $5^{\circ }$, ${1.8}^{\circ }$]
Multi-TE SE (Reference T2 mapping) (8min08s)	FOV = 26cm × 32cm, In-plane resolution = 2.5mm × 2.5 mm Parallel imaging factor = 2, Slice thickness = 5mm, Bandwidth = $\pm$62.5kHz, TR=1.8s TE = [20, 60, 80, 120] ms
STE-DWI (Reference ADC mapping) (2min52s)	FOV = 32cm × 32cm, Resolution = 2.5mm × 2.5 mm, Parallel imaging factor = 2, Slice thickness = 5mm, Bandwidth = $\pm$62.5kHz, TR=4s, Diffusion direction = R/L, TM=100ms, TE =40ms, b= [50, 100, 200(2), 400(4), 600(6), 800(8)] s/mm2
STEM (22min56s)	TM = 25ms, TE = 49ms	FOV = 32cm × 32cm, Resolution = 2.5mm × 2.5 mm Parallel imaging factor = 2, Slice thickness = 5mm, Bandwidth = $\pm$62.5kHz, TR=4s Diffusion direction = R/L
	TM = 100ms, TE = 40ms
	TM = 100ms, TE = 50ms
	TM = 100ms, TE = 65ms
	TM = 500ms, TE = 40ms
	TM = 500ms, TE = 50ms
	TM = 500ms, TE = 65ms
	TM = 1000ms, TE = 40ms