Table 3.

Group effects on fractional anisotropy (FA) and mean diffusivity (MD) for each region of interest at p < 0.05. There were significant decreases in FA in the left ALIC in chronic kidney disease (CKD) and transplant groups compared to control group. There was a significant increase in MD in the left ALIC and left optic radiation in the transplant group (ALIC = Anterior limb of the internal capsule, PLIC = Posterior limb of the internal capsule).

Brain Region	Group	Mean difference from controls	95% CI		p	Mean difference from controls	95% CI		p
		Fractional Anisotropy (FA)				Mean Diffusivity (MD)
Left ALIC	CKD	−0.0859	−0.127	−0.044	<0.001*	0.032	−0.001	0.066	0.06
	Transplant	−0.0973	−0.157	−0.038	0.002*	0.075	0.027	0.124	0.003*
Right ALIC	CKD	−0.021	−0.066	0.024	0.4	−0.012	−0.059	0.035	0.6
	Transplant	−0.055	−0.120	0.010	0.09	0.006	−0.061	0.074	0.9
Left PLIC	CKD	0.020	−0.014	0.055	0.2	−0.043	−0.077	−0.010	0.01*
	Transplant	−0.028	−0.077	0.021	0.3	−0.028	−0.065	0.030	0.5
Right PLIC	CKD	−0.007	−0.043	0.029	0.7	−0.036	−0.065	−0.006	0.02*
	Transplant	−0.048	−0.099	0.003	0.07	−0.003	−0.046	0.039	0.9
Left Optic	CKD	0.011	−0.028	0.051	0.6	−0.016	−0.058	0.027	0.5
Radiation	Transplant	−0.010	−0.067	0.048	0.7	−0.069	0.007	0.130	0.03*
Right Optic	CKD	−0.03	−0.086	0.027	0.3	−0.006	−0.054	0.043	0.8
Radiation	Transplant	0.009	−0.072	0.090	0.8	−0.000	−0.084	0.056	0.7