Table 1.
Demographics and baseline ophthalmic measurements from African descent and European descent individuals within diagnostic groups
Healthy Eyes | Glaucoma Suspect Eyes | Glaucoma Eyes | ANOVA* | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
AD | ED | All | P- value |
AD | ED | All | P- value |
AD | ED | All | P- value |
P-v alue |
|
Number of patients | 27 | 42 | 69 | 54 | 72 | 126 | 47 | 43 | 90 | ||||
Number of eyes | 42 | 82 | 124 | 94 | 133 | 227 | 95 | 82 | 177 | ||||
Sex, % female | 74 | 73 | 73.5 | 0.40 | 70 | 62 | 66 | 0.03 | 55 | 51 | 53 | 0.02 | 0.03 |
Age at baseline (years) |
64 ± 12 | 54 ± 12 | 59 ± 12 | 0.01 | 68 ± 11 | 68 ± 10 | 68 ± 11 | 0.70 | 67 ± 9 | 73 ± 12 | 70 ± 11 | 0.01 | <0.001 |
Median Number of visits |
3 (3, 4) | 5 (3, 9) | 5 (3,9) | 0.007 | 6 (3, 10) | 4 (3, 9) | 5 (3,10) | 0.20 | 8 (3, 10) | 8 (4, 10) | 8 (3,10) | 0.30 | 0.01 |
Mean Followup time (years) | 2.9 ± 1.2 | 1.9 ± 1.2 | 2.4 ± 1.22 | <0.001 | 2.8 ± 1.2 | 2.5 ± 1.2 | 2.6 ± 1.2 | 0.14 | 3.5 ± 0.8 | 3.2 ± 1.04 | 3.35 ± 1.01 | 0.01 | 0.007 |
Axial length (mm) | 23.7 ± 0.9 | 23.7 ± 0.8 | 23.7 ± 0.85 | 0.50 | 24.04 ± 1.04 | 24.1 ± 1.0 | 24.07 ± 1.01 | 0.70 | 23.8 ± 1.3 | 23.8 ± 1.2 | 23.8 ± 1.25 | 0.04 | 0.05 |
Disc area (mm2) | 2.08 ± 0.33 | 2.05 ± 0.41 | 2.07 ± 0.35 | 0.62 | 2.10 ± 0.41 | 2.03 ± 0.52 | 2.06 ± 0.48 | 0.39 | 2.17 ± 0.5 | 2.12 ± 0.62 | 2.15 ± 0.53 | 0.33 | 0.43 |
VF Mean deviation (dB) | 0.22 (−1.43, 2.1) |
−0.44 (−2.36, −2.29) |
−0.11 (−2.36, 2.1) |
0.02 | −0.17 (−4.8, −2.7) |
0.1 (−3.9, 2.7) |
−0.03 (−4.8,2.7) |
0.27 | −7.95 (−33.69, −0.51) |
−8.3 (−29.17, −.67) |
−8.3 (−33.69, −0.51) |
0.40 | <0.001 |
CCT (μm) | 528.5 ± 31.5 | 561.3 ± 38.6 | 544.9 ± 35.4 | <0.001 | 535.5 ± 42.3 | 553.4 ± 37.7 | 544.4 ± 41.2 | 0.001 | 525.0 ± 37.0 | 573.4 ± 41.0 | 549.2 ± 40.0 | 0.02 | 0.006 |
Mean IOP during follow-up (mmHg) | 14.3 ± 2.4 | 14.5 ± 2.8 | 14.4 ± 2.6 | 0.60 | 16.0 ± 4.2 | 17.1 ± 4.2 | 16.55 ± 4.2 |
0.06 | 14.8 ± 3.5 | 13.8 ± 3.8 | 14.3 ± 3.6 | 0.07 | 0.007 |
Abbreviations: VF, visual field; CCT, central corneal thickness, IOP, intraocular pressure. Variability measurements are ± SD, ranges or 95 percent confidence intervals. Wilcoxon rank sum test P-values reported representing the differences between AD and ED eyes.
P-values represent differences across diagnostic groups.