Figure 4. Liver and colon distribution of pCQ in colitis mice.
Animals treated with a single oral dose of pCQ and HCQ (30 mg/kg CQ equivalent) were sacrificed at pre-determined time points and total HCQ levels measured in liver and colon. Results are shown as concentration of HCQ in the tissues ± SD (n=3). pCQ data show the total (polymer-bound + free) HCQ blood concentration.