Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Non-compartmental blood pharmacokinetic analysis in colitis mice
| Pharmacokinetic parameter | HCQ | pCQ |
|---|---|---|
| Cmax (ng/mL) | 2,343 ± 46 | 12.2 ± 1.7 |
| t1/2 (h) | 5.6 ± 1.9 | 11.7 ± 3.6 |
| tmax (h) | 3.3 ± 1.2 | 4.7 ± 3.1 |
| AUC0-last (h×ng/mL) | 26,446 ± 507 | 161 ± 8 |
| AUC0- ∞ (h×ng/mL) | 28,182 ± 1476 | 231 ± 49 |
| Cl/F (L/h/kg) | 1.1 ± 0.1 | 134 ± 27 |
| MRT (h) | 6.8 ± 0.6 | 9.9 ± 0.7 |
