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Liver and colon pharmacokinetic parameters in colitis mice.
| Pharmacokinetic parameter | Liver HCQ | pCQ | Colon HCQ | pCQ |
|---|---|---|---|---|
| Cmax (ng/mL) | 12,807±3703 | 220.2±102.7 | 10,304 ± 746 | 7,121 ± 2,984 |
| tmax (h) | 2.0±0.0 | 0.5±0.0 | 8.0±0.0 | 8.0±0.0 |
| AUC0-last (h×ng/mL) | 167,944 ± 19,302 | 1,547 ± 100 | 166,377 ± 14,873 | 93,088 ± 34,403 |
| AUC0- ∞ (h×ng/mL) | 175,852 ± 18,362 | 1,659 ± 78 | 208,917 ± 55,806 | 94,515 ± 35,363 |
