Table 1.

Comparison of T₁, T₂, T₁-normalized MTR_asym and contributions from MTR asymmetry in T₁-normalized decoupled amide, amine, guanidinium, NOE and semisolid macromolecular MT (MTC_asym) effects toward T₁-normalized MTR_asym at 3.5 ppm in white matter (WM) and gray matter (GM) of normal and ischemic brains.

		Normal	Ischemia
T1 (s)	WM	1.363 ± 0.009	1.367 ± 0.016
	GM	1.656 ± 0.017***	1.713 ± 0.018***†††
T2 (ms)	WM	50.9 ± 0.5	49.2 ± 0.7†††
	GM	53.4 ± 0.5***	54.4 ± 0.9***†††
MTRasym (%/s)	WM	−3.88 ± 0.28	−5.93 ± 0.34†††
	GM	−1.92 ± 0.52***	−3.49 ± 0.71***†††
Amide_3.5ppm (%/s)	WM	2.08 ± 0.20	1.02 ± 0.09†††
	GM	2.00 ± 0.23	0.90 ± 0.10**†††
Amine_2.75ppm (%/s)	WM	0.15 ± 0.04	0.02 ± 0.01†††
	GM	0.14 ± 0.04	0.02 ± 0.01†††
Guanidinium _2.0ppm (%/s)	WM	0.24 ± 0.03	0.30 ± 0.04††
	GM	0.17 ± 0.02***	0.20 ± 0.03***†
NOE_−1.6ppm (%/s)	WM	−0.001 ± 0.000	−0.003 ± 0.002††
	GM	−0.001 ± 0.000	−0.002 ± 0.001†
NOE_−3.5ppm (%/s)	WM	−4.42 ± 0.58	−4.62 ± 0.18
	GM	−3.38 ± 0.42***	−3.33 ± 0.13***
MTCasym (%/s)	WM	−1.79 ± 0.88	−2.67 ± 0.38†
	GM	−0.89 ± 0.87*	−1.51± 0.44***

Mean ± standard deviation were shown. Paired t-tests were performed with

^***p<0.001,

^**p<0.01 indicating significant difference between WM and GM, and

^†††p<0.001,

^††p<0.01,

^†p<0.05 indicating significant difference between normal and ischemic tissues.