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Percentage of patients with adverse effects observed in the COMPARZ study
| ADVERSE EFFECT | PAZOPANIB | SUNITINIB |
|---|---|---|
| Fatigue | ||
| Any grade | 50% | 63% |
| Grade 3–4 | 10% | 17% |
| Hand-foot syndrome | ||
| Any grade | 29% | 50% |
| Grade 3–4 | 6% | 11% |
| Stomatitis | ||
| Any grade | 14% | 27% |
| ALTb | 60% | 43% |
| Fatal AEas | 2% | 3% |
| Fatal treatment-related AEs | 3 cases | 8 cases |
aAE: adverse events; bALT: alanine aminotransferase
