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NOLC1 knockdown significantly decreased cell viability of A549/MDR cells after multidrug treatments. A549/MDR cells were transfected with siNOLC1 or NC for 48 h after treatment with 5-FU, paclitaxel, mitomycin, vinorelbine tartrate, DDP and gemcitabine hydrochloride. CCK-8 assay was used to assess the drug cytotoxicities in A549/MDR cells. Data were expressed as means ± SD of at least three experiments. *p < 0.05, **p < 0.01 versus A549/MDR + NC
