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. 2018 Nov 27;15(11):e1002705. doi: 10.1371/journal.pmed.1002705

Table 3. Model performance by age.

This table details the accuracy, sensitivity, specificity, precision, and recall for 8 classifiers (Table 1) and for 4 age ranges found in evaluation of 162 home videos with an average length of 2 minutes. We also provide the IRA, which indicates the frequency with which the model results from all 3 raters’ feature tags agreed on class. The top-performing classifier was LR5, which yielded an accuracy of 88.9%, sensitivity of 94.5%, and specificity of 77.4%. Other notable classifiers were SVM5 and LR10, which yielded 85.4% and 84.8% accuracy, respectively. These 3 best-performing classifiers showed improved classification power within certain age ranges.

Age group Statistic ADTree8 ADTree7 SVM5 LR5 LR9 SVM12 SVM10 LR10
Overall
(116 ASD, 46 non-ASD, 64.4% male)
Sensitivity 100% 94.5% 100% 94.5% 100% 100% 100% 100%
Specificity 22.4% 37.3% 54.9% 77.4% 31.4% 0% 17.6% 51.0%
Accuracy 76.1% 76.3% 85.4% 88.9% 78.4% 71.6% 73.9% 84.8%
IRA 76.1% 67.5% 68.4% 71.7% 75.9% 71.6% 79.5% 70.9%
Precision 74.3% 76.3% 82.3% 89.7% 76.0% 71.6% 72.4% 82.0%
UAR 61.2% 65.9% 77.5% 86.0% 65.7% 50% 58.8% 75.5%
≤2 years
(17 ASD, 20 non-ASD, 56.8% male)
Sensitivity 100% 100% 100% 93.3% 100% 100% 100% 100%
Specificity 14.2% 18.2% 38.1% 77.3% 22.7% 0% 14.3% 47.6%
Accuracy 50% 51.4% 62.9% 83.8% 54.1% 40.5% 50.0% 96.2%
IRA 53% 48.6% 45.7% 51.4% 48.6% 100% 66.7% 100%
Precision 45.5% 45.5% 51.9% 73.7% 46.9% 45.9% 45.4% 57.7%
UAR 57.1% 59.1% 69.1% 85.3% 61.4% 50.0% 57.2% 73.8%
>2 years and ≤4 years
(39 ASD, 17 non-ASD, 66.1% male)
Sensitivity 100% 97.3% 100% 91.8% 100.0% 100% 100% 100%
Specificity 23.6% 50% 66.7% 73.7% 38.9% 0% 22.2% 58.8%
Accuracy 76.4% 50% 88.9% 85.7% 80.4% 66.7% 74.5% 86.8%
IRA 74.5% 81.8% 63.0% 75.0% 76.8% 100% 85.4% 77.4%
Precision 74.5% 80.0% 85.7% 87.2% 77.6% 69.6% 72.5% 83.7%
UAR 61.8% 73.7% 83.4% 82.8% 69.5% 50.0% 61.1% 79.4%
>4 years and ≤6 years
(34 ASD, 8 non-ASD, 61.9% male)
Sensitivity 100% 96.8% 100% 96.9% 100.0% 100% 100% 100%
Specificity 40.0% 60% 72.7% 90.9% 40.0% 0% 18.2% 50.0%
Accuracy 85.4% 87.8% 92.9% 95.3% 85.7% 74.4% 79.1% 88.1%
IRA 85.4% 78.0% 78.6% 79.1% 85.7% 93.0% 76.7% 71.4%
Precision 83.8% 88.2% 91.2% 96.9% 84.2% 80.9% 78.0% 86.5%
UAR 70.0% 78.4% 86.4% 93.9% 70.0% 50.0% 59.1% 75.0%
>6 years (26 ASD, 1 non-ASD, 74.1% male) Sensitivity 100% 84.6% 100% 96.2% 100% 100% 100% 100%
Specificity 0% 0% 0% 0% 0% 0% 0% 0%
Accuracy 96.2% 81.5% 96.2% 92.6% 96.2% 96.2% 96.2% 96.3%
IRA 96.2% 70.4% 96.2% 81.5% 96.2% 100% 100% 85.2%
Precision 96.3% 95.7% 96.3% 96.2% 96.3% 96.3% 96.3% 96.3%
UAR 50.0% 42.3% 50.0% 48.1% 50.0% 50.0% 50.0% 50.0%

Abbreviations: ADTree7, 7-feature alternating decision tree; ADTree8, 8-feature alternating decision tree; ASD, autism spectrum disorder; IRA, interrater agreement; LR5, 5-feature logistic regression classifier; LR9, 9-feature logistic regression classifier; LR10, 10-feature logistic regression classifier; SVM5, 5-feature support vector machine; SVM10, 10-feature support vector machine; SVM12, 12-feature support vector machine; UAR, unweighted average recall.