Table 3. Sensitivity and odds ratio of a positive colonflag for colorectal cancer or an advanced precancerous lesion in all study patients, by patient subgroup.
Group | N | ColonFlag Mean (SD) |
CRC/Advanced Precancerous Lesion | Specificity 95% | Specificity 90% | ||
---|---|---|---|---|---|---|---|
Sensitivity | Odds Ratio | Sensitivity | Odds Ratio | ||||
All Patients | 17,676 | 56.8 (18.5) | 1074 | 8.1 (6.4–9.8) | 1.7 (1.3–2.1) | 16.8 (14.5–19.0) | 1.8 (1.5–2.1) |
Average Risk | 12,251 | 56.8 (17.9) | 550 | 8.3 (5.7–10.8) | 1.7 (1.1–2.3) | 16.1 (12.9–19.6) | 1.7 (1.3–2.2) |
Family History | 3,808 | 52.9 (18.1) | 213 | 8.6 (4.7–13.6) | 1.8 (0.9–3.0) | 16.5 (11.6–22.0) | 1.8 (1.2–2.5) |
Personal History | 1,617 | 59.5 (19.4) | 311 | 4.6 (2.3–7.3) | 0.9 (0.4–1.5) | 8.7 (5.6–12.5) | 0.9 (0.5–1.3) |