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. 2018 Nov 27;13(11):e0207848. doi: 10.1371/journal.pone.0207848

Table 3. Sensitivity and odds ratio of a positive colonflag for colorectal cancer or an advanced precancerous lesion in all study patients, by patient subgroup.

Group N ColonFlag
Mean (SD)
CRC/Advanced Precancerous Lesion Specificity 95% Specificity 90%
Sensitivity Odds Ratio Sensitivity Odds Ratio
All Patients 17,676 56.8 (18.5) 1074 8.1 (6.4–9.8) 1.7 (1.3–2.1) 16.8 (14.5–19.0) 1.8 (1.5–2.1)
Average Risk  12,251 56.8 (17.9) 550  8.3 (5.7–10.8) 1.7 (1.1–2.3) 16.1 (12.9–19.6) 1.7 (1.3–2.2)
Family History  3,808 52.9 (18.1) 213  8.6 (4.7–13.6) 1.8 (0.9–3.0) 16.5 (11.6–22.0) 1.8 (1.2–2.5)
Personal History  1,617 59.5 (19.4) 311  4.6 (2.3–7.3) 0.9 (0.4–1.5) 8.7 (5.6–12.5) 0.9 (0.5–1.3)