Table 1. Percentage cure induced by benznidazole after long-term treatment of mice infected with Cl Brener wild-type, TcRAD51-/- or TcRAD51ox cells.
T.cruzi samples infecting mice | Number of mice | Number of positive mice | Percentage cure |
---|---|---|---|
WT | 14 | 1 | 92.6 |
TcRAD51+/- | 14 | 2 | 85.7 |
TcRAD51over | 12 | 6 | 50 |
*p < 0.05 vs. mice infected with wild-type parasites. Data were analyzed by Fisher’s exact test.