Table 5.
Pathways Analysis of Genes with dysregulated DMPs.
| Pathway (BioSystems) | Source | No. of genes | FDR P-value |
|---|---|---|---|
| Neutrophil degranulation | REACTOME | 138 | 9.20E-10 |
| Innate Immune System | REACTOME | 293 | 4.08E-09 |
| Hematopoietic cell lineage | KEGG | 40 | 8.88E-07 |
| Hemostasis | REACTOME | 150 | 3.16E-05 |
| Extracellular matrix organization | REACTOME | 80 | 1.54E-04 |
| Signalling events mediated by focal adhesion kinase | Pathway Interaction Database | 24 | 1.97E-04 |
| Phospholipase D signalling pathway | KEGG | 46 | 3.31E-04 |
| B cell receptor signalling pathway | KEGG | 28 | 3.31E-04 |
| Regulation of RAC1 activity | Pathway Interaction Database | 19 | 3.82E-04 |
| Cytokine Signalling in Immune system | REACTOME | 166 | 4.14E-04 |