Fig. 8. In vivo assessment of typical yeast and filamentous C. auris cell virulence in a mouse skin infection model.

a 1 × 10⁷ typical yeast or filamentous cells were inoculated onto the skin of 2–5-day-old mice. After 24 h of infection, mice were humanely euthanized. Histopathological PAS sections of infected skin tissues were used for microscopy assays. Scale bar represents 10 μm. b Scanning electron microscope (SEM) images of infected skin tissues. 4 × 10⁶ typical yeast or filamentous cells were inoculated onto the skin of 2–5-day-old mice. After 24 h of infection, mice were euthanized humanely. Infected skin tissues were used for SEM assays. Scale bar represents 5 μm