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. 2018 Nov 21;9:1650. doi: 10.3389/fphys.2018.01650

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Copyright © 2018 Zhang, Huang, Cai, Jiang, Xu, Zhou, Cao, Hultström, Tian and Lai.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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OST attenuates renal EMT in obstructive kidneys. Representative micrographs (A) and quantification (B,C) for E-cadherin and Vimentin in the obstructed kidneys from different groups as indicated. Arrows indicate immunostaining positive tubular epithelial cells. Scale bar = 100 μm. Representative bands (D) and western blots analyses (E,F) of E-cadherin and Vimentin in kidneys from the indicated groups. Data are expressed as mean ± SEM. ^∗P < 0.05 versus Sham + Vehicle; ^#P < 0.05 versus UUO + Vehicle.