Figure 2.

Expression Profiling of the Changes in circRNAs in Meningitic E. coli-Infected Primary hBMECs

(A) Heatmap showing unsupervised clustering of significantly expressed circRNAs from primary hBMECs in the meningitic E. coli infection groups compared with the control groups. The expression profiles are displayed with three samples in each group. Dark green represents high and pale green represents low relative expression. (B) Volcano plot of the upregulated and downregulated circRNAs from primary hBMECs in the meningitic E. coli infection group compared with the control group. p < 0.05 was considered statistically significant.