Table 1.
The Most Significantly Changed circRNAs in Primary hBMECs in Response to Meningitic E. coli (>4-fold)
| circRNA ID | Fold Change | Chromosome | Start Site | End Site | Strand | Genomic Length (bp) | Spliced Length (bp) | Gene ID |
|---|---|---|---|---|---|---|---|---|
| circ_0014254 | 8.48 | chr18 | 37,084,124 | 37,173,081 | + | 88,957 | 76,366 | ENSG00000150477 |
| circ_0030423 | 6.86 | chr4 | 39,737,419 | 39,774,933 | + | 37,514 | 336 | ENSG00000078140 |
| circ_0001409 | 5.41 | chr10 | 76,036,007 | 76,058,783 | + | 22,776 | 22,776 | – |
| circ_0003433 | 5.21 | chr11 | 68,429,574 | 68,433,838 | + | 4,264 | 4,138 | ENSG00000162337 |
| circ_0035876 | 5.04 | chr7 | 152,273,704 | 152,315,338 | − | 41,634 | 5,776 | ENSG00000055609 |
| circ_0030790 | 5.00 | chr4 | 83,272,086 | 83,279,114 | − | 7,028 | 7,028 | – |
| circ_0029917 | 4.87 | chr4 | 143,415,476 | 143,415,771 | + | 295 | 295 | ENSG00000109458 |
| circ_0038415 | 4.80 | chr8 | 55,941,854 | 55,947,723 | + | 5,869 | 5,869 | – |
| circ_0003467 | 4.57 | chr11 | 68,583,042 | 68,596,218 | + | 13,176 | 13,176 | ENSG00000110075 |
| circ_0019064 | 4.55 | chr1 | 233,198,938 | 233,227,371 | − | 28,433 | 8,711 | ENSG00000135749 |
| circ_0024628 | 4.55 | chr2 | 174,223,032 | 174,229,451 | − | 6,419 | 6,419 | – |
| circ_0001582 | 4.48 | chr10 | 92,648,211 | 92,650,517 | + | 2,306 | 223 | ENSG00000138160 |
| circ_0001726 | 4.40 | chr10 | 97,656,284 | 97,662,968 | + | 6,684 | 6,684 | – |
| circ_0006937 | 4.36 | chr14 | 20,996,208 | 20,996,711 | + | 503 | 503 | ENSG00000165792 |
| circ_0028050 | 4.04 | chr3 | 179,378,340 | 179,386,629 | + | 8,289 | 8,289 | ENSG00000171109 |
| circ_0000206 | 4.03 | chr10 | 110,593,072 | 110,598,290 | + | 5,218 | 1,740 | ENSG00000108055 |
| circ_0036105 | −6.95 | chr7 | 22,219,865 | 22,318,037 | − | 98,172 | 69,625 | ENSG00000136237 |
| circ_0001639 | −6.93 | chr10 | 94,441,895 | 94,500,327 | + | 58,432 | 58,432 | – |
| circ_0024411 | −6.10 | chr2 | 15,488,893 | 15,539,356 | − | 50,463 | 17,793 | ENSG00000151779 |
| circ_0033002 | −5.39 | chr6 | 107,503,656 | 107,533,610 | + | 29,954 | 29,663 | ENSG00000112320 |
| circ_0020478 | −5.13 | chr1 | 63,478,763 | 63,490,218 | − | 11,455 | 11,455 | ENSG00000142856 |
| circ_0037938 | −5.03 | chr8 | 15,623,079 | 15,673,836 | + | 50,757 | 11,622 | ENSG00000104723 |
| circ_0008815 | −4.92 | chr15 | 63,529,013 | 63,563,008 | + | 33,995 | 33,995 | ENSG00000140455 |
| circ_0000395 | −4.76 | chr10 | 124,038,514 | 124,046,724 | − | 8,210 | 7,159 | ENSG00000182022 |
| circ_0020149 | −4.70 | chr1 | 47,260,288 | 47,260,539 | − | 251 | 251 | ENSG00000123473 |
| circ_0018492 | −4.56 | chr1 | 21,001,198 | 21,050,994 | − | 49,796 | 49,796 | ENSG00000075151 |
| circ_0017073 | −4.47 | chr1 | 1,495,484 | 1,529,331 | + | 33,847 | 17,157 | ENSG00000160072 |
| circ_0005524 | −4.43 | chr12 | 56,643,402 | 56,645,353 | − | 1,951 | 1,951 | ENSG00000110955 |
| circ_0021024 | −4.31 | chr20 | 18,441,592 | 18,443,464 | − | 1,872 | 1,872 | ENSG00000089091 |
| circ_0007911 | −4.26 | chr14 | 90,578,105 | 90,618,045 | − | 39,940 | 39,940 | ENSG00000165914 |
| circ_0014803 | −4.12 | chr19 | 11,397,243 | 11,397,597 | − | 354 | 354 | – |
| circ_0040941 | −4.04 | chrX | 155,506,897 | 155,545,277 | − | 38,380 | 31,714 | ENSG00000185973 |