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. 2018 Nov 20;2(22):3126–3136. doi: 10.1182/bloodadvances.2018024851

Table 2.

FVIII deficiency did not improve the viability of Plg−/−mice

Group No. of mice in cohort No. of mice euthanized/dead within 168 d (%) Cause of death/euthanasia Distribution of dead mice (%)
WT 30 0 (0) Not applicable Not applicable
F8−/− 43 4 (9) Unknown 4 (100)
Plg−/− 23 18 (78) RP/wasting 17 (94)
Unknown 1 (6)
F8−/−/Plg−/− 26 22 (85) RP/wasting 20 (91)
Unknown 2 (9)

Gross examination was used to determine cause of euthanasia/death.

RP, rectal prolapse.