Table 1.

Substituents of reversible radiolabeled EGFR tyrosine kinase inhibitors.

#	R1	R2	X1	X2	X3	X4	Ref
1			H	H	F	Cl	[22,23]
2			H	H	18F	Cl	[24,25]
3			H	H	H		[26]
4			H	H	H	Br	[27,28,29]
5			H	H	H	Br	[30]
6			H	H	H	Cl	[33]
7			H	H	F	Cl	[34]
8			H	H	H	Br	[27]
9			H	H	18F	Cl	[25]
10			H	H	18F	Cl	[25]
11			H	H	18F	Cl	[35]
12			18F	H	Cl	Cl	[36]
13			H	CF3	H	18F	[36]
14			H	H	18F	H	[36,37]
15			H	18F	H	H	[37]
16			18F	H	H	H	[37]
17			H	H	18F	H	[37]
18			H	18F	H	H	[37]
19			18F	H	H	H	[37]
20		H	H	H	F	Cl	[38]
21			H	H	H	125I	[39]
22			H	H	H	123I	[40]
23		H	H	H	H	124I	[41]
24		H	H	H	F	Cl	[42]
25		H	H	H	H	Br	[42]
26		H	H	H	F	Cl	[42]