Table 2.

Cytotoxic activity (IC₅₀ µg/ml) of compounds 1-4 against human cancer and non-cancer cell lines.

Extracts	IC50 (µg/mL)
	KB	MCF7	CaSki	HCT116	MRC5
Flavokawin B (1)	5.7 ± 0.4	49.3 ± 1.8	31.1 ± 1.3	6.4 ± 0.2	17.2 ± 0.5
5 ,6-Dehydrokawain (2)	20.7 ± 0.9	> 100	> 100	> 100	> 100
Pinostrobin chalcone (3)	6.2 ± 0.2	7.3 ± 0.6	7.7 ± 0.2	54.1 ± 4.6	7.9 ± 0.8
Alpinetin (4)	>100	> 100	>100	39.6 ± 2.0	> 100
Doxorubicina	0.27 ± 0.01	0.05 ± 0.01	0.18 ± 0.06	0.24 ± 0.04	0.40 ± 0.03

^a Doxorubicin was used as the reference compound.