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. 2010 Nov 3;15(11):7861–7870. doi: 10.3390/molecules15117861

Table 1.

Different Components and Activities of Herba Epimedii.

Component Anti-oxidative Activity Reference
Total Flavonoid of Epimedium(TFE) 1. Inhibition of croton oil-induced ear edema and granuloma. [7]
2. Inhibition of acetic acid-induced vascular permeability.
3. Inhibition of carrageenin-induced hind paw edema.
4. Inhibition of primary and secondary inflammation in adjuvant arthritis.
5. Inhibition of prostaglandin E and malondialdehyde product.
6. Enhancement of catalase.
7. Protection of H2O2-induced lesions in cardiocytes including inhibition of cardiocyte proliferation and increase of cardiocyte apoptosis. [8,9]
Icarrin 1. Protection against free radical-induced damage of DNA. [10]
2. Protection against free radical-induced peroxidation of polyunsaturated fatty acids in low-density lipoprotein and cellular membrane [11]
3. Protection against H2O2-induced cell oxidative injury in vein endothelial cells. [17]
4. Protection against β-amyloid neurotoxicity [20,21]
Polysaccharide 1. Reduction of serum and liver levels of lipoperoxide in aged mice and rats and lipofuscin in cardiac muscle of aged mice. [23,24]
2. Increase in activities of superoxidase dismutase and glutathione peroxidase
Vitamin C 1. Maintainence of normal vasodilatory mechanism controlled by endothelial cells. [25]
2. Reduction of blood pressure.
3. Enhancement of iron absorption in gastrointestinal tract.