Total Flavonoid of Epimedium(TFE) |
1. Inhibition of croton oil-induced ear edema and granuloma. |
[7] |
2. Inhibition of acetic acid-induced vascular permeability. |
3. Inhibition of carrageenin-induced hind paw edema. |
4. Inhibition of primary and secondary inflammation in adjuvant arthritis. |
5. Inhibition of prostaglandin E and malondialdehyde product. |
6. Enhancement of catalase. |
7. Protection of H2O2-induced lesions in cardiocytes including inhibition of cardiocyte proliferation and increase of cardiocyte apoptosis. |
[8,9] |
Icarrin |
1. Protection against free radical-induced damage of DNA. |
[10] |
2. Protection against free radical-induced peroxidation of polyunsaturated fatty acids in low-density lipoprotein and cellular membrane |
[11] |
3. Protection against H2O2-induced cell oxidative injury in vein endothelial cells. |
[17] |
4. Protection against β-amyloid neurotoxicity |
[20,21] |
Polysaccharide |
1. Reduction of serum and liver levels of lipoperoxide in aged mice and rats and lipofuscin in cardiac muscle of aged mice. |
[23,24] |
2. Increase in activities of superoxidase dismutase and glutathione peroxidase |
Vitamin C |
1. Maintainence of normal vasodilatory mechanism controlled by endothelial cells. |
[25] |
2. Reduction of blood pressure. |
3. Enhancement of iron absorption in gastrointestinal tract. |