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. 2010 Dec 8;15(12):8973–8987. doi: 10.3390/molecules15128973

Table 2.

Concentration of ibandronate standard and co-crystal samples 1-3, 6, 7, 1a-3a, 6a and 7a in acceptor solutions of PAMPA plates. Data for PAMPA were calculated from 5 experiments.

Compound Conc. [μg/mL]
IBN monosodium salt 2.4
IBN+Ph-gal 1:1 (1) 2.4
IBN+Ph-gal 1:2 (2) 2.1
IBN+Ph-gal 1:3 (3) 2.06
IBN+Ph-gal+MeOH 1:2 (6) 2.2
IBN+Ph-gal+MeOH 1:3 (7) 2.01
IBN+Ph-gal 1:1 (1:6) (1a) <2
IBN+Ph-gal 1:2 (1:6) (2a) <2
IBN+Ph-gal 1:3 (1:6) (3a) <2
IBN+Ph-gal+MeOH 1:2 (1:6) (6a) <2
IBN+Ph-gal+MeOH 1:3 (1:6) (7a) <2