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Schematic representation the origin of sensory nerve fibers that innervate normal intervertebral discs. In the normal intervertebral disc, innervation is restricted to the outer layers of the AF and consists of small nerve fibers (yellow and green) and some large fibers forming mechanoreceptors (red). AF: annulus fibrosus; DRG: dorsal root ganglion; NP: nucleus pulposus.
